Consulting for Biotech & Pharmaceutical Companies
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Therapeutic Project Support
- Identifying/tracking/optimizing SAR and ADME trends within project data sets
- Structure-based modeling and virtual screening using protein structures
- Assessment/ranking of potential chemotypes using computational medicinal chemistry
- Custom analog design to improve compound profile (ex. selectivity and solubility) while maintaining potency
Screening Collection Design / Assembly
- Identification of target family interaction motifs
- Selection of chemical descriptors and generation of design space
- Identification, filtering, and prioritization compound source pools
- Design/selection of final screening collections
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